A Macrocycle-Mediated Protein Cage

Ronan J. Flood; Aurélien Thureau; Peter B. Crowley

doi:10.1021/acsmacrolett.4c00656

A Macrocycle-Mediated Protein Cage

Ronan J. Flood
, Aurélien Thureau
, Peter B. Crowley

Cellular & Molecular Medicine

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

Abstract

Engineered protein cages are of great interest considering their diverse applications in delivery and catalysis. Here, we describe macrocycle-triggered icosahedral cage assembly of a designed β-propeller. Cage assembly was evidenced by small-angle X-ray scattering and X-ray crystallography.

Original language	English
Pages (from-to)	1686-1690
Number of pages	5
Journal	ACS Macro Letters
Volume	13
Issue number	12
DOIs	https://doi.org/10.1021/acsmacrolett.4c00656
Publication status	Published - 17 Dec 2024

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10.1021/acsmacrolett.4c00656

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title = "A Macrocycle-Mediated Protein Cage",

abstract = "Engineered protein cages are of great interest considering their diverse applications in delivery and catalysis. Here, we describe macrocycle-triggered icosahedral cage assembly of a designed β-propeller. Cage assembly was evidenced by small-angle X-ray scattering and X-ray crystallography.",

author = "Flood, \{Ronan J.\} and Aur{\'e}lien Thureau and Crowley, \{Peter B.\}",

note = "Publisher Copyright: {\textcopyright} 2024 The Authors. Published by American Chemical Society.",

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doi = "10.1021/acsmacrolett.4c00656",

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AU - Flood, Ronan J.

AU - Thureau, Aurélien

AU - Crowley, Peter B.

PY - 2024/12/17

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N2 - Engineered protein cages are of great interest considering their diverse applications in delivery and catalysis. Here, we describe macrocycle-triggered icosahedral cage assembly of a designed β-propeller. Cage assembly was evidenced by small-angle X-ray scattering and X-ray crystallography.

AB - Engineered protein cages are of great interest considering their diverse applications in delivery and catalysis. Here, we describe macrocycle-triggered icosahedral cage assembly of a designed β-propeller. Cage assembly was evidenced by small-angle X-ray scattering and X-ray crystallography.

UR - https://www.scopus.com/pages/publications/85210273516

U2 - 10.1021/acsmacrolett.4c00656

DO - 10.1021/acsmacrolett.4c00656

M3 - Article

C2 - 39592260

AN - SCOPUS:85210273516

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VL - 13

SP - 1686

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JO - ACS Macro Letters

JF - ACS Macro Letters

IS - 12

ER -

A Macrocycle-Mediated Protein Cage

Abstract

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