3d printing of cell spheroids within self-healing hydrogels

Andrew C. Daly; Matthew D. Davidson; Kwang Hoon Song; Jason A. Burdick

3d printing of cell spheroids within self-healing hydrogels

Andrew C. Daly
, Matthew D. Davidson
, Kwang Hoon Song
, Jason A. Burdick

University of Pennsylvania

Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review

Abstract

Cell spheroids are increasingly used as building blocks in the engineering of tissues for therapeutics or disease models, as they mimic the cellular and extracellular interactions present in native tissues and organs [1]. While it has been established that spheroids can be fused together to form macroscale tissues [2], methods for precisely controlling their positioning and subsequent assembly within 3D are lacking. Here, we report the development of a 3D printing process that permits high-precision patterning of cell spheroids into self-healing hydrogels, including with open-channel structures for the introduction of drugs for screening.

Original language	English
Title of host publication	Society for Biomaterials Annual Meeting and Exposition 2019
Subtitle of host publication	The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
Publisher	Society for Biomaterials
Pages	34
Number of pages	1
ISBN (Electronic)	9781510883901
Publication status	Published - 2019
Externally published	Yes
Event	42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States Duration: 3 Apr 2019 → 6 Apr 2019

Publication series

Name	Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume	40
ISSN (Print)	1526-7547

Conference

Conference	42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
Country/Territory	United States
City	Seattle
Period	3/04/19 → 6/04/19

Cite this

Daly, A. C., Davidson, M. D., Song, K. H., & Burdick, J. A. (2019). 3d printing of cell spheroids within self-healing hydrogels. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting (pp. 34). (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40). Society for Biomaterials.

Daly, Andrew C. ; Davidson, Matthew D. ; Song, Kwang Hoon et al. / 3d printing of cell spheroids within self-healing hydrogels. Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 2019. pp. 34 (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium).

@inproceedings{f6014ceb451e455b8e0924b766221954,

title = "3d printing of cell spheroids within self-healing hydrogels",

abstract = "Cell spheroids are increasingly used as building blocks in the engineering of tissues for therapeutics or disease models, as they mimic the cellular and extracellular interactions present in native tissues and organs [1]. While it has been established that spheroids can be fused together to form macroscale tissues [2], methods for precisely controlling their positioning and subsequent assembly within 3D are lacking. Here, we report the development of a 3D printing process that permits high-precision patterning of cell spheroids into self-healing hydrogels, including with open-channel structures for the introduction of drugs for screening.",

author = "Daly, \{Andrew C.\} and Davidson, \{Matthew D.\} and Song, \{Kwang Hoon\} and Burdick, \{Jason A.\}",

note = "Publisher Copyright: {\textcopyright} 2019 Omnipress - All rights reserved.; 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence ; Conference date: 03-04-2019 Through 06-04-2019",

year = "2019",

language = "English",

series = "Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium",

publisher = "Society for Biomaterials",

pages = "34",

booktitle = "Society for Biomaterials Annual Meeting and Exposition 2019",

}

Daly, AC, Davidson, MD, Song, KH & Burdick, JA 2019, 3d printing of cell spheroids within self-healing hydrogels. in Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, vol. 40, Society for Biomaterials, pp. 34, 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence, Seattle, United States, 3/04/19.

3d printing of cell spheroids within self-healing hydrogels. / Daly, Andrew C.; Davidson, Matthew D.; Song, Kwang Hoon et al.
Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 2019. p. 34 (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40).

Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review

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T1 - 3d printing of cell spheroids within self-healing hydrogels

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AU - Davidson, Matthew D.

AU - Song, Kwang Hoon

AU - Burdick, Jason A.

PY - 2019

Y1 - 2019

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AB - Cell spheroids are increasingly used as building blocks in the engineering of tissues for therapeutics or disease models, as they mimic the cellular and extracellular interactions present in native tissues and organs [1]. While it has been established that spheroids can be fused together to form macroscale tissues [2], methods for precisely controlling their positioning and subsequent assembly within 3D are lacking. Here, we report the development of a 3D printing process that permits high-precision patterning of cell spheroids into self-healing hydrogels, including with open-channel structures for the introduction of drugs for screening.

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M3 - Conference Publication

AN - SCOPUS:85065401911

T3 - Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium

SP - 34

BT - Society for Biomaterials Annual Meeting and Exposition 2019

PB - Society for Biomaterials

T2 - 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence

Y2 - 3 April 2019 through 6 April 2019

ER -

Daly AC, Davidson MD, Song KH, Burdick JA. 3d printing of cell spheroids within self-healing hydrogels. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials. 2019. p. 34. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium).

3d printing of cell spheroids within self-healing hydrogels

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