My research is primarily focused on the use of functional genomics approaches to understand the molecular basis of human disease. This work involves the identification of genes, whose expression patterns are altered under disease conditions, determining their disease-association and analysing their functional significance. My main research interests in which I have active programmes are:   1. Nucleic acid-based diagnostics assay development for infectious disease pathogen detectionI have a long-standing, ongoing research programme focused on the design, development and clinical validation of nucleic acid-based diagnostics assays for infectious disease.  This is a research area, in which I am co-inventor of 8 granted patents, and over 50 filed patent applications.  Licenses have been granted to four IVD companies to exploit co-invented patented technologies.2. span style=color: black; line-height: normal;Cancer small RNA biomarker discovery and nucleic acid-based diagnostic assay development This ongoing research programmes aims to identify and detect small  regulatory  span style=color: rgb(0, 0, 0); line-height: normal;RNA  span style=color: black; line-height: normal;molecules and somatic cell mutations associated with cancer for diagnosis, therapeutic monitoring and disease management.  3. Molecular and cellular basis of complications of pregnancy and labour This research involves investigation of the molecular and cellular basis of complications of pregnancy and parturition to understand the underlying mechanisms involved in the process of labour, in reproductive tissues, including in particular myometrium.   4. Cellular interactions between novel biomaterials and vascular cells. Investigation of the molecular and cellular interactions between novel biomaterials with vascular cells and tissues has as a major goal, understanding and modulating the bodys response to implant materials.