Personal profile
Research Interests
I am a medical doctor specialised in pharmacology and toxicology, with a research focus on neuroscience and translational studies of chronic pain and associated neuropsychiatric disorders. My work explores the relationship between chronic pain, mood disorders, and cognitive dysfunction using an integrated approach that combines behavioural neuroscience, pharmacology, and molecular biology.
My research employs advanced experimental methods, including behavioural testing, neurochemical analyses, and genetically modified rodent models, to identify novel therapeutic targets. A key area of interest is the investigation of emerging cannabinoid-based therapies. Through interdisciplinary collaborations, I aim to clarify the neurobiological mechanisms linking pain and psychiatric disorders and to support the development of innovative treatment strategies.
Education/Academic qualification
MD, PhD
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 5 Gender Equality -
SDG 7 Affordable and Clean Energy
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Collaborations and top research areas from the last five years
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Antinociceptive and neuromodulatory effects of the scorpion venom tetrapeptide tetrascorpin-1 in a long-lasting pain hypersensitivity model in mice
Pagano, S., Limongelli, R., Moslah, W., Saada, M. C., Manzo, I., Bonsale, R., Teweldemedhin, M. M., Fusco, A., Guida, F., Belardo, C., Morace, A. M., Perrone, M., Ricciardi, F., Pierretti, G., Vastarella, M. G., Infantino, R., Srairi-Abid, N., Maione, S., Palazzo, E. & Luongo, L., Dec 2025, In: Toxicon. 268, 108611.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access -
Editorial: Pain and pain-related neuropsychiatric disorders: from mechanistic insights to innovative therapeutic strategies
Infantino, R., Turco, F., Guida, F. & Llorente-Berzal, Á., 2025, In: Frontiers in Pharmacology. 16, 1593890.Research output: Contribution to a Journal (Peer & Non Peer) › Editorial
Open Access -
Lighting the shades of hidden pain: a role for spinal cord neurons and microglia in vestibulodynia
Infantino, R., Gargano, F., Boccella, S., Belardo, C., Morace, A. M., Guida, F., Maione, S. & Luongo, L., 1 Oct 2025, In: Neural Regeneration Research. 20, 10, p. 2898-2900 3 p.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access3 Citations (Scopus) -
Potentiation of mitochondrial function by mitoDREADD-Gs reverses pharmacological and neurodegenerative cognitive impairment in mice
Pagano Zottola, A. C., Martín-Jiménez, R., Lavanco, G., Hamel-Côté, G., Ramon-Duaso, C., Rodrigues, R. S., Mariani, Y., Khan, M., Drago, F., Jean, S., Río, I. B. D., Jimenez-Blasco, D., Egaña-Huguet, J., Eraso-Pichot, A., Beriain, S., Cannich, A., Vidal-Palencia, L., Infantino, R., Julio-Kalajzić, F. & Gisquet, D. & 14 others, , Sep 2025, In: Nature Neuroscience. 28, 9, p. 1844-1857 14 p.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
2 Citations (Scopus) -
The Effect of Cannabidiol on Nociceptive Behaviour and the Endocannabinoid System in an Incisional Wound Model
Redmond, M. C., Healy, C. R., Hopkins, M., Infantino, R., Gethin, G., Pandit, A. & Finn, D. P., 24 Dec 2025, In: Pharmaceuticals.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review