Accepting PhD Students

PhD projects

Protein-based materials are the future of the biomedical and biotech industries. The Crowley laboratory is developing new methods of controlling protein self-assembly, which provides the cornerstone for this important field. We seek talented and highly-motivated BSc PhD graduates to join our SFI-funded team.

Over the past 15 years, the Crowley laboratory has developed the interface between supramolecular chemistry and structural biology, showing how synthetic receptors can induce protein assembly. Supramolecular Protein Chemistry is now a recognized field.

Calculated based on number of publications stored in Pure and citations from Scopus

Personal profile

Biography

After graduating with first class honours in chemistry Peter joined the laboratory of Prof. G. W. Canters at Leiden University, The Netherlands. Working with his advisor Prof. M. Ubbink, he used NMR spectroscopy to study transient protein interactions involved in electron transport. This research was summarized in Accounts of Chemical Research (2003). From the Netherlands Peter headed south for sunnier climes. With a Marie Curie Postdoctoral fellowship he joined the lab of Prof. M. A. Carrondo at Universidade Nova de Lisboa, Portugal. During this time he further developed his interest in molecular recognition. In particular, he demonstrated the importance of cation-pi interactions in protein-protein interfaces.In 2006, Peter returned to Ireland, working as a lecturer in Biochemistry at University College Dublin, and since 2008 as a lecturer in Chemistry at Galway. He was promoted in 2014 to Senior Lecturer and in 2017 to Personal Professor. Current interests include protein assembly using the tools of supramolecular chemistry. For more information see Public - No restrictionations. His research on protein - cailxarene recognition and assembly was summarized in Accounts of Chemical Research (2022).

Research Interests

- Molecular Recognition - Protein Interactions- Self Assembly - Supramolecular Chemistry- Macrocycles- Structural Biology- NMR spectroscopy X-ray crystallography - In-cell NMR spectroscopy- PEGylationA recent essay on host - guest chemistry:a target=_blank rel=nofollow href=https:pubs.acs.orgdoifull10.1021acs.cgd.3c00985https:pubs.acs.orgdoifull10.1021acs.cgd.3c00985 Review paper on ~10 years of protein - calixarene research at Galway.a target=_blank rel=nofollow href=https:pubs.acs.orgdoifull10.1021acs.accounts.2c00206https:pubs.acs.orgdoifull10.1021acs.accounts.2c00206 Textbook on Supramolecular Protein Chemistrya target=_blank rel=nofollow href=https:books.rsc.orgbooksedited-volume858Supramolecular-Protein-Chemistry-Assemblyhttps:books.rsc.orgbooksedited-volume858Supramolecular-Protein-Chemistry-Assembly Video by Ciara Kyne and CELT on protein interactions in cell extractsa target=_blank rel=nofollow href=https:www.youtube.comwatch?v=_549N4wHCjkhttps:www.youtube.comwatch?v=_549N4wHCjk Highlight of our Nature Chemistry 2012 papera target=_blank rel=nofollow href=https:www.youtube.comwatch?v=pOTWEPF925chttps:www.youtube.comwatch?v=pOTWEPF925c Video by James Ward and William Smith for distil life exhibition in 2011a target=_blank rel=nofollow href=https:vimeo.com32684138https:vimeo.com32684138

Teaching Interests

Peter contributes to various lecture and practical courses in GY301 and GY318, including: CH101 General chemistry CH202 Organic Chemistry practical classes CH333 Experimental Chemistry I CH3101 Computers and Chemical Research CH311 Organic Chemistry CH4101 Research project CH4115 Biopharmaceutical Chemistry CH4116 Biopharmaceutical Dissertation CH4117 Biopharmaceutical Work Placement CH438 Bioorganic Chemistry

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

B.Sc.,Ph.D.

External positions

Personal Professor, University of Galway

16 Sep 2008 → …

Accepting PhD Students

  • Accepting PhD Students

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