Research output per year
Research output per year
Accepting PhD Students
PhD projects
Join the XII ECMNP organised by our group at httpsecmnp2021.squarespace.com
Our research interest focus on the specialized metabolites, also called natural products, produced by marine organisms and especially marine invertebrates. We have expertise on the purification by HPLC and structure elucidation by NMR and MS of these small molecules. Such natural products may find applications in the pharmaceutical or cosmetical sectors through established collaborations. But we are also engaged in several projects in chemical ecology in order to understand their metabolic pathways but also their ecological role in the environment.
2015-: Established Professor in Marine Biodiscoveryat NUI Galway2012: Professor in Marine Natural Product Chemistry at University Nice Sophia Antipolis, France2004: Lecturer in Marine Natural Product Chemistryat University Nice Sophia Antipolis, France2002: Post-Doctorate at CEA Saclay, France2002: PhD in Organic Chemistry at University Paris Descartes, Franceunder the supervision of Henri-Philippe HUSSON1999: Master Degree in Organic Chemistry fromUniversity Paris Descartes, France1996-1998: Teacher at French School La Condamine Quito, Ecuador1996: Agregation in Chemistry at Ecole Normale Superieure de Cachan, France
Our research focuses on the specialized metabolites, also called natural products, produced by marine organisms and especially marine invertebrates like sponges, zoantharians, soft corals but also algae, microalgae, or cyanobacteria. While our main playground for biodiscovery is the North-eastern Atlantic and especially the Irish waters from the seashore until the deep sea, through collaborations with local marine biologists and ecologists, we work in the Caribbean and Mediterranean Seas or the Atlantic and Pacific Oceans. See our website at www.imbd.ieWe have expertise in the purification by HPLC and structure elucidation by NMR and MS of all types of specialized metabolites. Such natural products may find applications in the pharmaceutical, the cosmetical or agri-food sectors. Through the establishment of a National Marine Biodiscovery Laboratory in Ireland we strive for a strong collaboration between marine biologists, taxonomists, microbiologists, and chemists to organize a biological and chemical repository of marine products. We are also engaged in several projects in marine chemical ecology first to understand their metabolic pathways but also their ecological role in the environment. Although omnipresent, the chemical mediation in the marine environment is still very poorly understood. We develop new tools to point out the key role of some chemical cues in the structure of ecosystems. These findings may also find applications in several sectors like the aquaculture sector. These approaches are of special interest in the field of marine biotoxins. Under the impacts of anthropogenic activities and global changes the proliferation of non-indigenous species and especially toxic dinoflagellates and cyanobacteria affect local ecosystems through the production and release of specialized metabolites. The marine seafood sector is frequently under the threat of such toxic contamination. To address these basic and applied questions we want to apply the recent technological and more global approach called marine environmental metabolomics by mass spectrometry but also nuclear magnetic resonance.Keywords: Natural Product Chemistry,Bioactive Natural Products,Chemical Ecology,Marine Invertebrates,Sponges,Microalgae,Metabolic Pathways,Metabolomics
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
PhD
Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Thomas, O. (Primary Supervisor)
Activity: Other › Current Postgraduates (Research) Supervised
Thomas, O. (Primary Supervisor)
Activity: Other › Current Postgraduates (Research) Supervised
Thomas, O. (Reviewer)
Activity: Reviews and editorial work › Reviews & Editorial work
Thomas, O. (Other)
Activity: Other › Collaborations