Research output per year
Research output per year
Personal profile
Biography
Dr Syeda Masooma Naqvi is a Research Fellow at the University of Galway and an independent researcher in physiological mechanotransduction and musculoskeletal and cancer mechanobiology. She holds a BSc in Biomedical Science (major in Physiology), an MSc in Clinical Research, and a PhD in Regenerative Medicine from Trinity College Dublin, awarded without corrections. She also holds a Postgraduate Certificate in Innovation and Entrepreneurship from Trinity College Dublin.
Dr Naqvi's independent research programme, established in 2022, investigates how mechanical forces regulate physiological processes at the cellular level and how their dysregulation drives disease.
Her research has been recognised nationally with the Royal Academy of Medicine in Ireland Bronze Medal (2022). She has published 24 peer-reviewed papers, including first and joint-first author papers in Cell Reports, the American Journal of Physiology - Cell Physiology, and the Journal of Bone and Mineral Research Plus. She has secured independent competitive seed funding including an Irish Association for Cancer Research Seed Fund, and has (co)supervised 9 MSc and 4 PhD students to completion.
Research Interests
- Physiological mechanotransduction
- Musculoskeletal physiology and ageing
- Cancer mechanobiology and metastasis
- Ex vivo bone organ modelling
- 3D in vitro disease models
- Fragility fracture and osteoporosis
Education/Academic qualification
B.Sc., M.Sc., PhD
External positions
Research Fellow, University of Galway
1 Jun 2024 → …
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Early intermittent low-dose sclerostin antibody treatment promotes surface bone formation and reduces bone loss, but also decreases osteocyte apoptosis and mechanotransduction in ovariectomized rats: A pilot study
Naqvi, S. M., Ali, W., Allison, H., O'Sullivan, L. M., Holdsworth, G., Panadero-Perez, J. A., Schiavi-Tritz, J. & McNamara, L. M., Jun 2026, In: Bone Reports. 29, 101915.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access -
Generation of 3D humanized vascularized and mineralized bone mimetic model via endochondral ossification
Bukhari, M. M. M., Khabooshani, M., Naqvi, S. M. & McNamara, L. M., 1 Aug 2026, In: Stem Cell Research. 94, p. 103995 1 p.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access -
Mechanical loading under estrogen deficiency enhances mineralization and osteoblast maturation in an advanced 3D vascularized bone organoid driven by hypertrophy and apoptosis
Bukhari, M. M. M., Naqvi, S. M. & McNamara, L. M., Sept 2026, In: Journal of Biomechanics. 206, p. 1-11 11 p., 113529.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open AccessFile -
Osteoblasts exert a pro-tumorigenic effect on breast cancer spheroids through CXCL5/CXCR2 signalling in two-dimensional and three-dimensional bone mimetic cultures
Nano, S., Naqvi, S. M., Weiner, I., Volz, N., Kumar, V., Littlepage, L. E., McNamara, L. M. & Niebur, G. L., 18 Feb 2026, In: Journal of the Royal Society Interface. 23, 235, 20250753.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access -
Estrogen deficiency alters vascularization and mineralization dynamics: insight from a novel 3-D humanized and vascularized bone organoid model
Bukhari, M. M. M., Khabooshani, M., Naqvi, S. M. & McNamara, L. M., Mar 2025, In: American Journal of Physiology - Cell Physiology. 328, 3, p. C743-C756Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
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Research Staff Network(Internal) (External organisation)
Naqvi, M. (Member)
2026 → …Activity: Membership › Membership of network
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Diana Meriakri University of Galway
Naqvi, M. (Co-Supervisor)
2024 → 2025Activity: Other › Postgraduates Supervised
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European Society of Biomechanics (External organisation)
Naqvi, M. (Member)
2024 → 2027Activity: Membership › Membership of board
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European Association for Cancer Research (External organisation)
Naqvi, M. (Member)
1 Sept 2023 → 2027Activity: Membership › Membership of board
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Sailakshmi Senthilkumar University of Galway
Naqvi, M. (Primary Supervisor)
2022 → 2023Activity: Other › Postgraduates Supervised