Personal profile
Biography
Career profile: 1997-present: Permanent lecturer in Biochemistry amp; Head of the Molecular Glycobiotechnology Group, School of Natural Sciences, NUI, Galway 1993-1997: Research Group Leader, Dept. of Biochemistry, NUI Galway 1991-1993: Research Scientist (post-doctoral) University of Gent, Belgium, BSH Institut für Holzchemie, Hamburg, Germany amp; NUI Galway 2007: Diploma in French, NUI Galway PhD research (Biochemistry), University College Galway; B.Sc. (Biochemistry), University College Galway (Recipient of one of 10 University entrance scholarships) Brief Biography: Dr. Maria TuohyisPrincipal Investigator and head ofthe Molecular Glycobiotechnology Group (MGBG). Dr. Tuohyhas a strong track record in Glycobiotechnology and Enzyme Biotechnology, with ~25 years experience in fungal biology and biotechnology. A special focus ofthe research is on developing enabling technology for bioconversion of terrestrial plants and algae for biorefinery and bioenergy applications. This research encompasses protein biotechnology, molecular enzymology, proteomics, fungal genetics, biology and genomics, fermentation, analytical methods in glycobiology and protein biochemistry, development of novel energy systems, as well as key analytical methods to measure and characterize novel bioactive compounds from microbial, plant and marine sources. Understanding fungal biodiversity and the relationships between fungi and other organisms (terrestrial plants and marine life) forms a centraltheme that underpins the research on developing fungi as cell factories for production of enzymes andbioactives of biotechnological relevance.Research to date has involved ongoing collaboration with industry. Dr. Tuohy is one of 5 PIs in the EI-IDA supported, industry-led, national Technology Centre for Biorefining and Bioenergy (TCBB) and more recently, TCBB Resource. Through TCBB is involved in the European Bio-based Industries Consortium (BIC) and was a PI on the Technological Innovation workpackage of an EU FP7 INTERREG IVB NWE Programme (ReNEW), which was coordinated by The Queens University Belfast and involved a consortium of RTD, Industry and regional development organisations across NW Europe. Dr. Tuohy is also a co-PI on Pillar 5 of the recent national Dairy Processing Technology Centre (DPTC; 25m funding), since February 2015, and a collaborating PI in the recent SFI-Industry supported Sustainable Energy amp; Fuel Efficiency Spoke in MaREI Research Centre. Dr. Tuohy amp; her group are members of the Energy Research Centre and Environmental Technologies PRA group, Ryan Institute, NUI Galway, Ireland. Dr. Tuohy has successfully mentored 33 PhD students to completion to-date, and was awarded a prestigious Presidents Award for Teaching Excellence in 2011-2012 by NUI Galway
Research Interests
Novel thermostable enzymes and non-catalytic proteins from fungal sources (Enzyme biodiscovery), especially biomass-modifying enzymes (carbohydrases, proteases, oxidoreductases), and cell wall disrupting proteins. Protein production, engineering and molecular genetics of thermophilic and mesophilic fungal species, their optimization and exploitation as cell factories for biotechnological applications; Structure-Function, enzymatic modification amp; mechanism of action of bioactive molecules from marine, fungal and terrestrial plant sources (Glycobioengineering); Enzymes as key biorefinery and green chemistry tools.
Teaching Interests
Biochemistry of Carbohydrates and (Glyco)proteins from eukaryotes (fungi, plants, marine algae, animalshumans) Understanding protein structure-function relationships through investigating enzymesenzyme systems Biodiversity, evolution and interactions of fungi with other host and non-host lifeforms, with a focus on terrestrial plants, marine algae and marine animals. Fungal and plant natural products. Modern analytical technologies (bioseparation and mass spectrometry) used in proteomics and secretomics approaches to understand biomolecule function in vitro and in vivo . Blended and innovative learning and training methodologies and their application to laboratory and non-laboratory teachingtraining in biochemistry to support student engagement, self-directed and peer learning and future career development.
Education/Academic qualification
B.Sc., Ph.D.
External positions
Research Scientist (post-doctoral) 1991-1993, University of Gent, Belgium, BSH Institut für Holzchemie, Hamburg, Germany & NUI Galway
Accepting PhD Students
- Accepting PhD Students
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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SDG 6 Clean Water and Sanitation
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SDG 7 Affordable and Clean Energy
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SDG 9 Industry, Innovation, and Infrastructure
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SDG 11 Sustainable Cities and Communities
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SDG 12 Responsible Consumption and Production
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SDG 13 Climate Action
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SDG 15 Life on Land
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Collaborations and top research areas from the last five years
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Decoding butyrate fermentation with glucose as a model substrate: Parameter optimization and metagenomic insights
Shi, X., Yasuda, S., Tuohy, M., Wang, Z., Hu, Y., Trably, E., Lens, P. N. L. & Zhan, X., Jan 2026, In: Bioresource Technology. 439, 133365.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access -
Enhancing biodegradability and biomethane potential of cattle paunch contents during anaerobic digestion through pre-treatment with the secretome of deep-sea Talaromyces stollii and rumen fluid
Dowd, B., O'Donovan, A., Gupta, V. K., O'Flaherty, V. & Tuohy, M. G., 5 Jun 2025, In: Bioresource Technology Reports.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open AccessFile1 Citation (Scopus) -
Optimization of protein quantification from soil samples
Waibel, M., Tuohy, M. G., Paterson, E., Thornton, B., Brennan, F. P. & Abram, F., 1 Oct 2025, In: European Journal of Soil Science.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open AccessFile1 Citation (Scopus) -
Exploring the Physicochemical Characteristics of Marine Protein Hydrolysates and the Impact of In Vitro Gastrointestinal Digestion on Their Bioactivity
Sharma, D., Gite, S. & Tuohy, M. G., Oct 2024, In: Marine Drugs. 22, 10, 452.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access5 Citations (Scopus) -
A biochemical approach to utilizing fish processing wastes as potential nutraceuticals
Sharma, D., Tuohy, M. & Gite, S., 2023, OCEANS 2023 - Limerick, OCEANS Limerick 2023. Institute of Electrical and Electronics Engineers Inc., (OCEANS 2023 - Limerick, OCEANS Limerick 2023).Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review
1 Citation (Scopus)
Activities
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Jeremy Brebion University of Galway
Tuohy, M. (Primary Supervisor)
2014 → 2024Activity: Other › Postgraduates Supervised
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Talaromyces emersonii enzyme Systems
Tuohy, M. (Other)
29 Aug 2012 → 2013Activity: Other › Patents & Licensing Agreements
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Ashish Rawson - with Dr. N. Brunton University of Galway
Tuohy, M. (Primary Supervisor)
2012 → 2024Activity: Other › Postgraduates Supervised
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Sarah Foley - with Prof. K. Sullivan University of Galway
Tuohy, M. (Primary Supervisor)
2011 → 2024Activity: Other › Postgraduates Supervised
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Deborah Waters - �with Dr. J. Donlon University of Galway
Tuohy, M. (Primary Supervisor)
2010 → 2024Activity: Other › Postgraduates Supervised