Personal profile
Biography
I am a biomedical researcher with a strong interest in understanding gene expression control mechanisms and developing therapeutic strategies for currently incurable diseases. I graduated in Biochemistry from the University of Córdoba and completed my PhD at the University of Galway in Dr Goljanek-Whysall’s group, supported by the Hardiman and Irish Research Council scholarships. My research specialises in epigenetic regulation and RNA-based therapeutics, with a particular focus on microRNAs and oxidised microRNAs (oxi-miRs) as emerging therapeutic targets. I also investigate mitochondrial homeostasis and its role in muscle dysfunction during ageing, cancer cachexia and neurodegenerative conditions.
My expertise spans microRNA biology, primary cell culture, animal models and omics-based approaches relevant to ageing, cachexia and neurodegeneration. I am currently a postdoctoral researcher on a JPND-funded international project developing RNA-based and gene-editing strategies for rare and neurodegenerative diseases, including Alzheimer’s disease.
I have published in leading journals and actively disseminate my research at international conferences. Alongside my research, I am committed to teaching, mentoring and fostering a positive and inclusive research culture, reflected on my contributions to undergraduate and postgraduate teaching and training of national and international students in laboratory-based research. I actively contribute to outreach and inclusivity initiatives, including my role as social media manager of REACT-Enlight Network and on the Equality, Diversity and Inclusion Committee at the University of Galway.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Research output
- 9 Article
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The role of microRNAs in regulating neuromuscular degeneration in Amyotrophic Lateral Sclerosis: PP IIF124
Outeiriño, L. R., Gonzalez-Ojeda, R., Sannicandro, A. J., Borja-Gonzalez, M. & Goljanek-Whysall, K., 2024, In: Free Radical Biology And Medicine. 218, p. 52 1 p.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
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miR-199A regulates muscle homeostasis in SOD1 mouse model of amyotrophic lateral sclerosis: PP IIB09
Outeiriño, L. R., Gonzalez-Ojeda, R., Sannicandro, A. J., Borja-Gonzalez, M. & Goljanek-Whysall, K., 2025, In: Free Radical Biology And Medicine. 233, p. S74Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
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oxi-miR-133 as a mediator of muscle loss in cancer cachexia: PP IIB07
Borja-Gonzalez, M., González-Ojeda, R., Bertazzoli, L., Sannicandro, A. J., Aljuaid, T., McDonagh, B. & Goljanek-Whysall, K., 2025, In: Free Radical Biology And Medicine. 233, p. S73-S74Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
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PERK orchestrates MERCS formation and mitochondrial remodelling promoting physiological adaptations during adaptive UPR signalling
Casas-Martinez, J. C., Xia, Q., Li, P., Borja-Gonzalez, M., Miranda-Vizuete, A., McDermott, E., Dockery, P., Quinlan, L. R., Goljanek-Whysall, K. & Samali, A., 2025, In: bioRxiv. p. 2025-01 2023 p.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
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Adaptive ER stress promotes mitochondrial remodelling and longevity through PERK-dependent MERCS assembly
Casas-Martinez, J. C., Xia, Q., Li, P., Borja-Gonzalez, M., Miranda-Vizuete, A., McDermott, E., Dockery, P., Quinlan, L. R., Goljanek-Whysall, K., Samali, A. & McDonagh, B., 1 Nov 2025, In: Cell Death & Differentiation.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
2 Citations (Scopus)
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SFFR biannual conference
Borja Gonzalez, M. (Conference Organising Committee Chairperson)
2025Activity: Participating in or organising an event › Organising a conference, workshop, ...
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Polish Academy of Sciences
Borja Gonzalez, M. (Visiting researcher)
2025Activity: Visiting an external institution › Visiting an external academic institution
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Satellite NRF2 meeting
Borja Gonzalez, M. (Conference Organising Committee Chairperson)
2025Activity: Participating in or organising an event › Organising a conference, workshop, ...
Prizes
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Poster award Prize at All Ireland RNA club conference, June 2024
Borja Gonzalez, M. (Recipient), 2024
Prize
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