Personal profile
Biography
My current role is Head of Strategic Research Award Life Cycle in the College of Business, Public Policy, and Law at University of Galway. I lead a team responsible for the expansion of research activity and impact across the College's three Schools. Prior to this role, I was a Senior Research Support Officer in the University's Research Office. I actively help researchers locate, plan for, and apply for research funding. Attached to this, I also assist researchers with a variety of the resources required to manage their research projects and personnel.
I moved to University of Galway (then NUI Galway) in 2007 while completing my doctoral work in the Molecular and Cellular Biology program at Arizona State University. My scientific research has focused on complex sugar structures (oligosaccharides and polysaccharides) and how they function in a variety of biological systems. Because they are part of every living organism, these complex sugars are vital to many aspects of health and often display variations under the influence of infection, disease or environmental stress. I have worked with carbohydrates in a variety of pursuits across glycomics, proteomics, biosensing and the development of high-throughput screening and analysis techniques. As a member of the Advanced Glycoscience Research Cluster (AGRC), I was involved in academic collaborations as well as industrial partnerships with companies including Randox and Bristol-Myers Squibb. I participated in the Centre for Bioanalytical Sciences (CBAS), an international academic-industrial partnership, where I worked primarily on the rapid detection of minute quantities of enzymes in complex media. I also discovered and characterized fungal enzymes which facilitate the selective removal of oligosaccharides from proteins. As part of the Regenerative Medicine Institute (REMEDI), I have studied the glycobiology of extracellular vesicles (including exosomes) and their potential as diagnostic and prognostic indicators of renal health through an HRB-funded project with members of Mayo Clinic and a Science Foundation Ireland TIDA. I was also involved in the launch of Aquila Bioscience, Ltd., a spinout life-science company from University of Galway.
Research Interests
As a biologist with experience spanning biochemistry and chemical biology, my research interests have always been diverse. General areas of interest include: Extracellular vesicles; Glycoconjugate characterization; Identification and control of pathogens; Novel carbohydrate-specific enzymes; Enhancement of data sets for cross-discipline access and transfer; Affinity-based analysis methods; Biosensors and applications of biosensing
Education/Academic qualification
Ph.D
Keywords
- Q Science (General)
- carbohydrates
- extracellular vesicles
- lectins
- affinity
- multiplexed analysis
- chemical biology
- funding
- impact
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 9 Industry, Innovation, and Infrastructure
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Extracellular vesicle glycosylation in transport, signaling, and function
Gerlach, J. Q., 1 Jan 2023, Translational Glycobiology in Human Health and Disease. Elsevier, p. 203-218 16 p.Research output: Chapter in Book or Conference Publication/Proceeding › Chapter › peer-review
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Lectins and their applications in biomedical research
Gerlach, J. Q., Flannery, A. & Kilcoyne, M., 1 Jan 2023, Translational Glycobiology in Human Health and Disease. Elsevier, p. 37-53 17 p.Research output: Chapter in Book or Conference Publication/Proceeding › Chapter › peer-review
2 Citations (Scopus) -
Bacterial Staining and Profiling for Glycan Interactions on Glycan Microarrays for t-Test Calculation
Gerlach, J. & Kilcoyne, M., 1 Jan 2022, Methods in Molecular Biology. Humana New York, Springer, p. 223-237 15 p. (Methods in Molecular Biology; vol. 2460).Research output: Chapter in Book or Conference Publication/Proceeding › Chapter › peer-review
Open Access -
Calculating Half Maximal Inhibitory Concentration (IC50) Values from Glycomics Microarray Data Using GraphPad Prism
Le Berre, M., Gerlach, J. Q., Dziembała, I. & Kilcoyne, M., 1 Jan 2022, Methods in Molecular Biology. Humana Press Inc., p. 89-111 23 p. (Methods in Molecular Biology; vol. 2460).Research output: Chapter in Book or Conference Publication/Proceeding › Chapter › peer-review
Open Access44 Citations (Scopus) -
Comparison of Single and Repeated Dosing of Anti-Inflammatory Human Umbilical Cord Mesenchymal Stromal Cells in a Mouse Model of Polymicrobial Sepsis
Fazekas, B., Alagesan, S., Watson, L., Ng, O., Conroy, C. M., Català, C., Andres, M. V., Negi, N., Gerlach, J. Q., Hynes, S. O., Lozano, F., Elliman, S. J. & Griffin, M. D., Apr 2022, In: Stem Cell Reviews and Reports. 18, 4, p. 1444-1460 17 p.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access16 Citations (Scopus)
Activities
- 1 Postgraduates Supervised
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Raymond OConnor University of Galway
Gerlach, J. (Primary Supervisor)
2017 → 2018Activity: Other › Postgraduates Supervised