Research output per year
Research output per year
Accepting PhD Students
PhD projects
Immunology, immunometabolism, cancer immunology, checkpoint blockade therapy, NK cells, ovarian cancer
Award-winning Immunologist skilled in cancer immunology, oncology, and immunometabolism. Proven track record of success in research with Public - No restrictionations in high-impact journals including Nature Immunology and the Journal of Experimental Medicine . Strong scientific writing skills with funding from the IRC, EACR, and BSI. Presented at national and international meetings, demonstrating strong oral communication skills. Currently working as a postdoctoral researcher in Biomedical Engineering at the University of Galway, Ireland.
I am interested in uncovering the mechanisms that promote immunosuppression in the tumour microenvironment. Natural Killer (NK) cells are cytotoxic lymphocytes that kill cancer cells through the release of IFNy and cytolytic perforins and granzymes. Within the tumour, NK cells express the inhibitory TIGIT, which suppresses NK cell activation and function upon binding to its ligand CD155. I am currently investigating the effects of TIGIT blockade on NK cell cytotoxicity against ID8 ovarian cancer cells in vitro. Future experiments will deliver anti-TIGIT antibodies to ovarian cancer-bearing mice to determine if this therapeutic strategy can impair tumour growth in vivo.
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
B,Sc., PhD.
Postdoctoral Researcher, University of Galway
17 Jul 2023 → …
Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Prendeville, H. (Other)
Activity: Other › Community Engagement/Outreach
Prendeville, H. (Participant)
Activity: Other › Education
Prendeville, H. (Participant)
Activity: Other › Education
Prendeville, H. (Other)
Activity: Other › Collaborations
Prendeville, H. (Recipient), Sep 2024
Prize: Honorary award
Prendeville, H. (Recipient), Sep 2024
Prize: Honorary award
Prendeville, H. (Recipient), Sep 2018
Prize: Honorary award