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Accepting PhD Students

PhD projects

The Death-Receptor Signalling Research Group studies the mechanism of signal transduction in order to understand the driving forces of cancer progression and identify targets for therapy. Based on this information we are developing novel therapeutics that can block pro-survival signalling and thus channel signal transduction towards apoptosis.

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Personal profile

Biography

Affiliation: Foundation ResearchLecturer in Cancer Biology, Discipline of Biochemistry, NUI, Galway, Director Blood Cancer Network Ireland, Director Blood Cancer Biobank Ireland, Principal investigator Cancer Niche Laboratory. Career information Dr. Szegezdi received her PhD in medical science in 2000 studying cell death signalling at the University of Debrecen, Hungary. She then joined the Cell Stress and Apoptosis Research laboratory led by Prof. Afshin Samali at the National University of Ireland, Galway in 2001 to study stress-induced cell death in heart and pancreatic cells. In 2010 she established her own research group as a Science Foundation Ireland Starting Investigator (SIRG) and an Irish Cancer Society Research Fellow focusing on how the tissues surrounding cancer cells protect the tumour from chemotherapeutics. She took up a university lecturer position in the Discipline of Biochemistry, National University of Ireland, Galway in 2011. In 2017, she received a Research Lectureship position in Cancer Biology,a position she currently holds. Shedirects the Masters degree programme on cancer research, co-PI in the Centre for Research Training in Genomics Data Science and co-ordinates the H2020-funded INTEGRATE programme within the Genomics CRT. Research and Clinical Interests:Research in Dr Szegezdis laboratory focuses on death receptor signal transduction and how death receptor signalling shapes the interaction between the tumour and its microenvironment. In this research, she co-ordinates the H2020-RISE research consortium, DISCOVER. The other research area of her laboratory is blood caner research, especially acute myeloid leukemia and the mechanism of drug resistance mediated by the bone marrow stroma, where AML cells reside. In this research, she directs the national research consortium, Blood Cancer Network Ireland and has established and leads a national biobank collecting blood cancer patient samples.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 7 - Affordable and Clean Energy
  • SDG 9 - Industry, Innovation, and Infrastructure

Related documents

Education/Academic qualification

M.Sc., Ph.D.

External positions

Associate Professor in Biochemistry, University of Galway

1 May 2022 → …

Accepting PhD Students

  • Accepting PhD Students

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