Accepting PhD Students

PhD projects

(1) Fully Funded PhD Scholarship in RNA-Based Molecular Machines and Computation: At its core, life is computation. Every cell is an intricate molecular processor, receiving inputs, modifying internal states, and producing outputs in a continuous, dynamic dialogue with its environment. But unlike silicon-based computers, biological computation does not rely on rigid logic gates or binary circuits. Instead, it is fluid, emergent, and deeply entangled with the materiality of molecules themselves. This project explores RNA not merely as an information carrier but as an active computational substrate—a material capable of self-assembly, transformation, and information processing. We aim to engineer RNA-based supramolecular machines, molecular constructs that interact via oligonucleotide exchange, forming programmable networks that process inputs, compute transitions, and reconfigure in response to molecular signals.

Calculated based on number of publications stored in Pure and citations from Scopus

Personal profile

Biography

Dr Effirul Ramlan is a Lecturer (Above the Bar) at the School of Computer Science, University of Galway. Prior to this role, he served as Genuity Science Lecturer at the UCD School of Medicine, Lecturer in Data Analytics at Ulster University (2019–2021), and Senior Lecturer in the Department of Artificial Intelligence at the University of Malaya (2009–2019). He obtained his PhD in Computer Science from the University of Southampton in 2009, specialising in the computational and theoretical development of nucleic acid computers as information processors.

Dr Ramlan’s research focuses on designing synthetic nucleic acid interfaces, including DNA and RNA nano-machines, capable of molecular-level information processing within biological systems.

He has published over 30 peer-reviewed journal articles and book chapters spanning both life sciences and computer science disciplines. Over the past decade, he has secured funding as Principal Investigator from various national and international research funding bodies.

Research Interests

The science of informed matter has led to the creation of self-organising, adaptive, and complex biocomputers. As a scientist specialising in biological computing, my research is dedicated to developing DNA-RNA interfaces capable of executing complex molecular-level information processing within biological systems.

My pioneering work includes novel molecular fabrication and programming techniques aimed at creating self-organising biomolecular computers. I explore unconventional computational models distinct from traditional silicon-based systems, providing new opportunities for advanced scientific applications, such as amorphous computation for theranostics systems. Additionally, I have developed a suite of computational tools focused on bioinformatics, particularly structural and sequence annotation and analysis. These tools have enabled novel insights into biomolecular structures and functions, thereby contributing significantly to our broader understanding of biological systems.

My research interests extend into evolutionary optimisation and bio-inspired algorithms, integrating artificial intelligence methodologies—particularly machine learning, including foundational models and reinforcement learning—to support diverse research activities in the life sciences. By connecting computer science methodologies with life science applications, my work seeks to drive groundbreaking discoveries in key areas, such as drug discovery, medical image analysis, and disease diagnosis.

Teaching Interests

Module Coordinator for:

  • CT417 - Software Engineering III
  • CT413 - Final Year Project (CS)
  • CT2101 - Object Oriented Programming I
  • CT5168 - Enterprise Java Programming
  • CT5178 - Computing Architecture & Operating Systems
  • CT3112 - Professional Skills 

 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 9 - Industry, Innovation, and Infrastructure

Education/Academic qualification

PhD

External positions

Genuity Science (Ireland) Lecturer (Genomics Data Science), University College Dublin

1 Apr 202131 Oct 2022

Lecturer in Data Analytics, Ulster University

1 May 201930 Apr 2021

Director of Research, Malaysia Genome Institute (MGI-NIBM)

1 Mar 201730 Apr 2019

Senior Lecturer (Artificial Intelligence), Universiti Malaya

10 Nov 200931 Mar 2019

Keywords

  • QA75 Electronic computers. Computer science
  • Artificial Intelligence
  • Reinforcement Learning
  • Amorphous Computation
  • Bioinformatics
  • Computational Biology
  • Q Science (General)
  • Synthetic Biology
  • Biological Computing
  • DNA / RNA Computers

Accepting PhD Students

  • Accepting PhD Students

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