Personal profile
Biography
2017 - Present:Lecturer in Organic Chemistry, NUI Galway 2014 - 2017:Research Officer, University of Bristol, Lab of V. Aggarwal 2012 - 2014:Associate Editor, Chemistry-A European Journal,Wiley-VCH 2012 - 2012:Assistant Editor, Angewandte Chemie,Wiley-VCH 2010 - 2012:LMU Research Fellow, LMU-Munich, Germany, Lab of D. Trauner 2006 - 2009:Postdoctoral Associate, University of WisconsinMadison, Lab of R. Raines 2002 - 2006:Ph.D., University of Bristol (2006), Lab. of V. Aggarwal 2002 - 2002:M.Sc. McGill University (2003), Lab of Y. Tsantrizos 1996 - 2000:B.A. Natural Science, Trinity College Dublin (2000), First Class, Gold Medal
Research Interests
Research in the Myers group lies at the interface between chemistry and biology. Current activities can be assignedto one or both oftwo themes: a) chemical biology of the extracellular matrix (ECM); b) novel methods for carbon-nitrogen bond formation.Chemical Biology of the Extracellular Matrix (ECM)Our goal is to elucidate in great detailthe mechanism of formation of advanced glycation endproducts (AGEs), specifically crosslinks derived from ternary reactions of glucose, lysine and arginine. We are also interested in exploring the biological implications of our findings, particularly the role AGEs in diabetes,and potential avenues for therapeutic interventions.In the area of regenerative medicine, we are interested in developing small-molecule building blocks and reagents for generating collagen-and elastin-like materials with desirable mechanical and biochemical properties.Novel Methods for Carbon-Nitrogen Bond FormationWe are interested in the design and developmentof main-group catalysts for the condensation of small-molecule carboxylic acids and amines. To support activities in our chemical biology theme, we are developing bioorthogonal reagents and methods for forming amide bonds involving large biomolecules. We are also exploring conceptually new ways of transforming azides.Group Website:a target=_blank rel=nofollow href=http:www.eddiemyerschemistry.comhttp:www.eddiemyerschemistry.com
Education/Academic qualification
BA., MSc., PhD
External positions
Research Officer, University of Bristol
1 Oct 2014 → 31 Aug 2017
Accepting PhD Students
- Accepting PhD Students
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Conformationally Controlled sp3-Hydrocarbon-Based α-Helix Mimetics
Dewis, L. I., Rudrakshula, M., Williams, C., Chiarparin, E., Myers, E. L., Butts, C. P. & Aggarwal, V. K., 5 Jun 2023, In: Angewandte Chemie - International Edition. 62, 23, e202301209.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access4 Citations (Scopus) -
Iterative synthesis of 1,3-polyboronic esters with high stereocontrol and application to the synthesis of bahamaolide A
Aiken, S. G., Bateman, J. M., Liao, H. H., Fawcett, A., Bootwicha, T., Vincetti, P., Myers, E. L., Noble, A. & Aggarwal, V. K., Feb 2023, In: Nature Chemistry. 15, 2, p. 248-256 9 p.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
36 Citations (Scopus) -
Bicyclic 5:6 Systems: Other Four Heteroatoms 2:2
Myers, E., 1 Jan 2022, Comprehensive Heterocyclic Chemistry IV. ElsevierResearch output: Chapter in Book or Conference Publication/Proceeding › Chapter › peer-review
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Bicyclic 5–6 Systems: Other Four Heteroatoms 2:2
Myers, E. L., 1 Jan 2021, Comprehensive Heterocyclic Chemistry IV. Elsevier, p. 500-564 65 p.Research output: Chapter in Book or Conference Publication/Proceeding › Chapter › peer-review
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Conformationally Controlled Linear and Helical Hydrocarbons Bearing Extended Side Chains
Guo, L., Dutton, O. J., Kucukdisli, M., Davy, M., Wagnières, O., Butts, C. P., Myers, E. L. & Aggarwal, V. K., 13 Oct 2021, In: Journal of the American Chemical Society. 143, 40, p. 16682-16692 11 p.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access8 Citations (Scopus)
Activities
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Roisin Leen
Myers, E. (Primary Supervisor)
2024 → …Activity: Other › Current Postgraduates (Research) Supervised
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Guillermo Palop University of Galway
Myers, E. (Primary Supervisor)
2023 → 2024Activity: Other › Postgraduates Supervised
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Lee-Ann Keane University of Galway
Myers, E. (Primary Supervisor)
2020 → 2024Activity: Other › Postgraduates Supervised
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Damian Jablonski University of Galway
Myers, E. (Primary Supervisor)
2018 → 2019Activity: Other › Postgraduates Supervised
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Ciaran Mc Grory
Myers, E. (Primary Supervisor)
1 Mar 2013 → 2024Activity: Other › Current Postgraduates (Research) Supervised