Personal profile
Biography
Dr Michael Conall Dennedy is a Consultant Endocrinologist at Galway University Hospitaland a Senior Lecturer in Therapeutics at NUI, Galway. He is a Galway graduate, completing a BSc in Pharmacology in 2000, MB, BAO, BCh in 2002, MD in Obstetricsin 2007 and PhD in Medicinein 2013. He trained through the HSEHRB National SpR Academic Fellowship Programme, anintegrated academic clinician scientist programme. Following this he completed a fellowship in endocrinology at the University of Cambridge and Addenbrookes hospital. He assumed his current post in February 2014.His research interests centre on the pathogenesis and treatment of functional adrenal tumours, both benign and malignant. He is a member of the European Network for the Study of Adrenal Tumour working Groups forAdrenocortical Carcinoma, Aldosterone Producing Adenomas, Phaeochromocytoma and Non Aldosterone Producing Adrenocortical Adenomas. He retains links with the Institute of Metabolic Science,University of Cambridge and has forgedcollaborations with the Centre for Endocrinology, Diabetes and Metabolism,University of Birmingham. He is also affiliated with the CURAM programme at NUI, Galway and the Translational Medical Device Laboratory.He is the NUI, Galway director for the WellcomeHRB Irish Clinical AcademicTraining (ICAT)Programme and a co-recepient of this award. He is also the director of the undergraduate MBPhD programme at NUI, Galway. He is the Specialty Director for Endocrinology forthe Royal College of Physicians of Irelands,International Clinical Fellows Programme.
Research Interests
Research interests centre on the diagnosis, pathogenesis and management of functional adrenal tumours, both benign and malignant. NIHSFI Tripartitie Award: The investigation of sub-ablative thermal therapy in primary aldosteronism. LifetimeCDT Award: The development of 3D and organoid cellcultures to investigate non particle uptake for thermal therapy of functioning adrenocortical tumours. Irish Endocrine Society Small Grants AwardIRCPGFOI Award: The role of LXRalpha and lipid metabolism in the therapeutics of adrenocortical carcinoma. Member of the European Network for the Study of Adrenal Tumour working Groups forAdrenocortical Carcinoma, Aldosterone Producing Adenomas, Phaeochromocytoma and Non Aldosterone Producing Adrenocortical Adenomas. Continued linksInstitute of Metabolic Science,University of Cambridge (Prof Mark Gurnell) Collaborations with the Centre for Endocrinology, Diabetes and Metabolism,University of Birmingham (Prof Wiebke Arlt), the Dept of Endocrinology at the Mayo Clinic Rochester (Prof Irina Bancos)and Kansas State University (Prof Punit Prakash). CURAM-funded investigatorat NUI, Galway. Partnership on thermal ablation device development with theTranslational Medical Device Laboratory.
Teaching Interests
Undergraduate Teaching: Therapeutics and Endocrinology to third science, and second,third and final medical years.Director of the integrated Undergraduate MBPhD Programme.Director and co-recepientof WellcomeHRB ICAT programme for NUI, Galway.
Education/Academic qualification
BSc, MB BAO BCh, MD, PhD, MRCPI.
BSc, MB BAO BCh, MD, PhD, MRCPI
Accepting PhD Students
- Accepting PhD Students
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Assessing the financial burden on patients and their households attending hospital clinics: a pilot cross-sectional study
Rabbitt, L., Curneen, J., Hobbins, A., Gillespie, P. & Dennedy, M. C., 22 Oct 2025, In: BMC Health Services Research. 25, 1, p. 1390Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
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Development and Characterization of 3-Dimensional Cell Culture Models of Adrenocortical Carcinoma
Feely, S., Mullen, N., Donlon, P. T., Reidy, E., Challapalli, R. S., Hassany, M., Sorushanova, A., Martinez, E. R., Owens, P., Quinn, A. M., Pandit, A., Harhen, B., Finn, D. P., Hantel, C., O'Halloran, M., Prakash, P. & Dennedy, M. C., 1 Jan 2025, In: Endocrinology (United States). 166, 1, bqae159.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access4 Citations (Scopus) -
Iron Oxide Nanoparticle Uptake, Toxicity, and Steroidogenesis in Adrenocortical Carcinoma Cells Using a Multicellular in vitro Model
Challapalli, R. S., Hong, C., Sorushanova, A., Covarrubias-Zambrano, O., Mullen, N., Feely, S., Covarrubias, J., Varghese, S., Hantel, C., Owens, P., O'Halloran, M., Prakash, P., Bossmann, S. & Dennedy, M., Aug 2025, In: International Journal Of Nanomedicine.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
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8543 Non-Specific Uptake Of Magnetic Iron Oxide Nanoparticles Into Adrenocortical Carcinoma Cells, Endothelium And Primary Monocytes
Challapalli, R. S., Sorushanova, A., Hong, C., Mullen, N. J., Feely, S., Covarrubias-Zambrano, O., Covarrubias, J., Varghese, S., Hantel, C., Owens, P., O’Halloran, M., Prakash, P., Bossmann, S. H. & Dennedy, M. C., 5 Oct 2024, In: Journal of the Endocrine Society.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
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Association of adrenal steroids with metabolomic profiles in patients with primary and endocrine hypertension
Knuchel, R., Erlic, Z., Gruber, S., Amar, L., Larsen, C. K., Gimenez-Roqueplo, A. P., Mulatero, P., Tetti, M., Pecori, A., Pamporaki, C., Langton, K., Peitzsch, M., Ceccato, F., Prejbisz, A., Januszewicz, A., Adolf, C., Remde, H., Lenzini, L., Dennedy, M. & Deinum, J. & 5 others, , 2024, In: Frontiers in Endocrinology. 15, 1370525.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access11 Citations (Scopus)
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Sarah Feely
Dennedy, C. (Primary Supervisor)
2024Activity: Other › Current Postgraduates (Research) Supervised
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Hong Cong
Dennedy, C. (Primary Supervisor)
2024Activity: Other › Current Postgraduates (Research) Supervised
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Nathan Mullen
Dennedy, C. (Primary Supervisor)
2024Activity: Other › Current Postgraduates (Research) Supervised
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Catriona Reddin
Dennedy, C. (Co-Supervisor)
2024Activity: Other › Current Postgraduates (Research) Supervised
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Irina Bancos, The Mayo Clinic Rochester, U.S.A.
Dennedy, C. (Other)
0001Activity: Other › Collaborations