Research output per year
Research output per year
Personal profile
Biography
PhD in Anaesthesia (Lung Biology) from NUI Galway in 2014. Worked on a European Respiratory Society fellowship at St Michael’s hospital, Toronto, studying novel techniques in stromal cell-immune cell interactions. Investigated biopharmaceuticals to treat pneumonia at TUS Midlands. Currently working as a Research fellow on European Defence Funding in the O'Toole group, University of Galway, working as lab, project, and programme manager for four separate EU projects. Skilled in pre-clinical research focusing on pulmonary and systemic sepsis rodent models, novel therapeutic investigation including cell therapies, and processing human samples to demonstrate physiological and immunological parameters of injury and repair. Lecturer, Postgraduate supervisor, Member of the Animal Welfare Committee, CMNHS Reserach Ethics Committee, and the university staff wellness committee.
Research Interests
Mesenchymal Stem Cells; MUSE Cells; Pulmonary Sepsis; Defence research for CBRN threats; COVID-19; Immunology;
Teaching Interests
Immunology; Gene and cell therapy; Respiratory Infection and disease; Laboratory sustainability
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
BSc. MSc.
External positions
Post doctoral researcher, Lecturer
Jun 2016 → Dec 2017
Post doctoral researcher, SickKids Foundation
Jul 2014 → Sep 2015
Research Fellow, St. Michael's Hospital, Toronto
May 2014 → May 2016
Research Scientist, Orbsen Therapeutics Ltd.
Oct 2013 → Apr 2014
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Multiple Dosing and Preactivation of Mesenchymal Stromal Cells Enhance Efficacy in Established Pneumonia Induced by Antimicrobial-Resistant Klebsiella pneumoniae in Rodents
Byrnes, D., Masterson, C. H., Gonzales, H. E., McCarthy, S. D., O’Toole, D. P. & Laffey, J. G., May 2023, In: International Journal of Molecular Sciences. 24, 9, 8055.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access6 Citations (Scopus) -
The Effects of the Pneumonia Lung Microenvironment on MSC Function
Liu, L., Fandiño, J., McCarthy, S. D., Masterson, C., Sallent, I., Du, S., Warren, A., Laffey, J. & O’Toole, D., 20 Sep 2024, In: Cells.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
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Nebulised mesenchymal stem cell derived extracellular vesicles ameliorate E. coli induced pneumonia in a rodent model
Gonzalez, H., McCarthy, S., Masterson, C., Byrnes, D., Sallent, I., Horan, E., Elliman, S. J., Vella, G., Mello, A. P., Silva, J. D., Krasnodembskaya, A. D., MacLoughlin, R., Laffey, J. G. & O’Toole, D., Dec 2023, In: Stem Cell Research and Therapy. 14, 1, 151.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access13 Citations (Scopus) -
Aerosol Delivery of a Novel Recombinant Modified Superoxide Dismutase Protein Reduces Oxidant Injury and Attenuates Escherichia coli Induced Lung Injury in Rats
McCarthy, S. D., Tilbury, M. A., Masterson, C. H., MacLoughlin, R., González, H. E., Laffey, J. G., Wall, J. G. & O’Toole, D., 1 Oct 2023, In: Journal of Aerosol Medicine and Pulmonary Drug Delivery. 36, 5, p. 246-256 11 p.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access -
Can nebulised heparin reduce acute lung injury in patients with SARS‑CoV‑2 requiring advanced respiratory support in Ireland: the CHARTER‑Ireland phase Ib/IIa, randomised, parallel-group, open-label study
Cosgrave, D., McNicholas, B., Hanley, C., Sheehan, J. R., Calpin, P., Kernan, M., Murphy, D., Alvarez‑Iglesias, A., Ferguson, J., Giacomini, C., Greene, C., Cody, C., McGeary, S., Murphy, M., Fitzgerald, M., Curley, G., Dixon, B., Smith, R. J., Masterson, C. & O’Toole, D. & 2 others, , Dec 2025, In: Intensive Care Medicine Experimental. 13, 1, 15.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access4 Citations (Scopus)
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Lanzhi Liu
Masterson, C. (Co-Supervisor)
2024Activity: Other › Current Postgraduates (Research) Supervised
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Karthick Vishal University of Galway
Masterson, C. (Primary Supervisor)
2021 → 2023Activity: Other › Postgraduates Supervised
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Sarah Crudden University of Galway
Masterson, C. (Primary Supervisor)
2006 → 2023Activity: Other › Postgraduates Supervised
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Elisabeth Baumann University of Galway
Masterson, C. (Other)
2019 → 2023Activity: Other › Postgraduates Supervised
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Daniel Walshe University of Galway
Masterson, C. (Other)
2016 → 2023Activity: Other › Postgraduates Supervised