Personal profile
Biography
Dr. Mai is an enthusiastic material chemist having 9 years of experience working on advanced polymer chemistry and self-assembly, surface functionalization of nanoparticles and multi-functional nanomaterials for biomedical applications. His main research interests focus on the exploitation of living radical polymerization and click chemistry to prepare well-defined stimuli-responsive polymeric nanomaterialshydrogels toward applications in biomedical field such as drug delivery and cancer immunotherapy. His goal is to use advanced polymer chemistry to molecularly engineer polymeric materials, achieving a highly multi-functional materials with unprecedented and on-demand characteristics. During his career, Dr. Mai has participated in several European and national projects in Europe on the development of novel nanomaterials for cancer treatment. He had been awarded an ADMIRE-Marie Skodowska-Curie Fellowship from November 1st, 2021, to October 31st, 2022) with a research grant focusing on the potential of combined photothermal therapy and controlled drug delivery in Glioblastoma treatment. In addition, he was the recipient of Travel grant for PepsiCo and New York Academy of Science STEM Symposium 2018 (2000 $) and the winner of First prize in the pitch challenge, Drug delivery, Micro- and Nano Sensors PhD Summer Schools, Denmark (2016). He is currently a LecturerAssistant Professor in Biomaterials Chemistry with permanent at the School of Biological and Chemical Science, University of Galway.
Research Interests
I am a passionate polymer chemist with more than 10 years of experiences working with different types of polymeric materials, ranging from nano- to macro-scale, as well as realizing their potentials for biomedical applications. I have been consistently interested in delivering novel nanomaterials to tackle different diseases with a strong focus on cancer, which has been a challenging disease for decades and requires an effective therapy urgently. My research encompasses different aspects in biomaterials development and applications, ranging from syntheses, characterizations to therapeutic validations. My research group is fascinated by the beauties of living radical polymerization, thus we use living radical polymerization as a workhorse to synthesize polymers with unprecedented control over their architectures and physicochemical properties. This, in turn, will allow for the possibility of the developed materials to meet all the demanding requirements for a specific application in drug delivery and biomedical field. Currently, my research interests are centered at four different pillars focusing on, but not limited to, cancer therapy. They include: i) Novel hybrid nanomaterials for combined cancer therapy and drug delivery, ii) Stimuli-responsive injectable hydrogelsnanoparticles to harness cancer immunotherapy, iii) Targeting polymer-drugs conjugate nanoparticulate systems, and iv) Understanding the interaction between polymeric nanoparticlesbiomaterials and living organism.I do believe in the values of multidisciplinary research and am always looking for the opportunities to build up a research group with diverse scientific backgrounds. I am always looking for new members and collaborators who shares with us this common interest to leverage chemistry and solve the real-world problems.
Teaching Interests
Polymer Chemistry and Nanochemistry
Education/Academic qualification
PhD
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Nanoplatforms for Magnetic-Photo-Heating of Thermo-Resistant Tumor Cells: Singular Synergic Therapeutic Effects at Mild Temperature
Mai, B. T., Fernandez-Cabada, T., Conteh, J. S., Nucci, G. E. P., Fiorito, S., Gavilán, H., Debellis, D., Gjurgjaj, L. & Pellegrino, T., 19 Dec 2024, In: Small. 20, 51, 2310522.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access10 Citations (Scopus) -
CuFeS2 Nanoparticles Functionalized with a Thermoresponsive Polymer for Photothermia and Externally Controlled Drug Delivery
Conteh, J. S., Nucci, G. E. P., Fernandez Cabada, T., Mai, B. T., Soni, N., De Donato, F., Pasquale, L., Catalano, F., Prato, M., Manna, L. & Pellegrino, T., 17 May 2023, In: ACS Applied Materials and Interfaces. 15, 19, p. 22999-23011 13 p.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access16 Citations (Scopus) -
Intranasal Polymeric and Lipid-Based Nanocarriers for CNS Drug Delivery
Maher, R., Moreno-Borrallo, A., Jindal, D., Mai, B. T., Ruiz-Hernandez, E. & Harkin, A., Mar 2023, In: Pharmaceutics. 15, 3, 746.Research output: Contribution to a Journal (Peer & Non Peer) › Review article › peer-review
Open Access91 Citations (Scopus) -
Scale-up approach for the preparation of magnetic ferrite nanocubes and other shapes with benchmark performance for magnetic hyperthermia applications
Gavilán, H., Rizzo, G. M. R., Silvestri, N., Mai, B. T. & Pellegrino, T., Mar 2023, In: Nature Protocols. 18, 3, p. 783-809 27 p.Research output: Contribution to a Journal (Peer & Non Peer) › Review article › peer-review
81 Citations (Scopus) -
Clickable Polymer Ligand-Functionalized Iron Oxide Nanocubes: A Promising Nanoplatform for 'Local Hot Spots' Magnetically Triggered Drug Release
Mai, B. T., Conteh, J. S., Gavilán, H., Di Girolamo, A. & Pellegrino, T., 2 Nov 2022, In: ACS Applied Materials and Interfaces. 14, 43, p. 48476-48488 13 p.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access17 Citations (Scopus)
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First Class Honor (Talented Program)Organic Chemistry
Mai, B. (Participant)
2011 → …Activity: Other › Education
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Royal Society of Chemistry (External organisation)
Mai, B. (Member)
0001Activity: Membership › Membership of board