Personal profile
Biography
since 2017: Senior Lecturer, NUI Galway since 2007: Lecturer in Inorganic Chemistry, NUI Galway 2004: Visiting Professor, Institute of Inorganic Chemistry of the University of Vienna, Austria 2002 - 2006: Privatdozent, University of Dortmund, Germany 2002: Habilitation, University of Dortmund, Germany 1995 - 1997: Postdoctoral fellow, McGill University, Montréal 1995: Dr. rer. nat. (PhD), University of Dortmund, Germany 1992: Dipl.-Chem, University of Dortmund, Germany
Research Interests
My research interests comprise Medicinal Inorganic Chemistry and Pharmaceutical Solid State Chemistry. Research activities in the area of Medicinal Inorganic Chemistry are centered on the synthesis and study of anticancer metallodrugs. A specific focus is on the development of new Pt(IV) anticancer pro-drugs with reduced side effects, metal complexes with receptor-specific carriers for target-delivery and selective accumulation into cancer tissue and on metal complexes that exhibit anticancer activity by irreversibly cleaving the tumour cell DNA. My research activities in the field of solid state chemistry of pharmaceuticals are aimed at improving the bioavailability and thus the therapeutic efficacy of poorly soluble drugs, including antibiotics, via co-amorphisation, co-crystallisation, control of crystal size and habit and polymorph control.
Teaching Interests
Inorganic Chemistry Bioinorganic Chemistry Medicinal Chemistry X-ray Crystallography
Education/Academic qualification
Ph.D., B.Sc.
External positions
Senior Lecturer, NUI Galway
1 Nov 2017 → …
Accepting PhD Students
- Accepting PhD Students
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 7 Affordable and Clean Energy
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SDG 9 Industry, Innovation, and Infrastructure
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Collaborations and top research areas from the last five years
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First crystal structure of an aspartame cocrystal
Fereidouni, N., Aljohani, M. & Erxleben, A., 29 Jul 2025, In: Crystal Growth and Design.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Stacking interactions in indomethacin solid-state forms
Fereidouni, N., Aljohani, M. & Erxleben, A., 10 Mar 2025, In: Crystal Growth and Design.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open AccessFile -
Understanding the synthon preferences in molecular ionic cocrystals of trimethoprim─An experimental and computational study
Refat, L. A. E. & Erxleben, A., 5 May 2025, In: ACS Omega.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Application of Sublimation in the Synthesis and Crystal Growth of Organosulfones
Alaa Eldin Refat, L., Karpinska, J., Konda, S., Simmie, J. M., Murphy, P. V., McArdle, P. & Erxleben, A., 25 Jun 2024, In: Chemistry - A European Journal. 30, 36, e202400672.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open Access2 Citations (Scopus) -
Auranofin loaded silk fibroin nanoparticles for colorectal cancer treatment
Pérez-Lloret, M., Reidy, E., Lozano-Pérez, A. A., Marchal, J. A., Lens, P. N. L., Ryan, A. & Erxleben, A., 1 Oct 2024, In: Drug Delivery And Translational Research.Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review
Open AccessFile1 Downloads (Pure)
Activities
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Maria Medeiros Macieira
Erxleben, A. (Primary Supervisor)
2024 → …Activity: Other › Current Postgraduates (Research) Supervised
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Husain Bazzaz Zadehgan
Erxleben, A. (Primary Supervisor)
2024 → …Activity: Other › Current Postgraduates (Research) Supervised
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Andrew Salmon
Erxleben, A. (Primary Supervisor)
2024 → …Activity: Other › Current Postgraduates (Research) Supervised
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Jose Domingo Arce Rubio
Erxleben, A. (Primary Supervisor)
2024 → …Activity: Other › Current Postgraduates (Research) Supervised
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Nidhi Singh
Erxleben, A. (Primary Supervisor)
2024 → …Activity: Other › Current Postgraduates (Research) Supervised